How do AI markings on screening mammograms correspond to cancer location?

This retrospective study compared the location of artificial intelligence (AI) markings on screening mammograms with cancer location on diagnostic mammograms and found that the AI markings corresponded to cancer location for all screen-detected cancers and 78% of the interval cancers with a high AI score.

Key points:

  • All screen-detected and 78% of the interval cancers with high AI risk score (AI score of 10) had AI markings in one or two views corresponding to the location of the cancer on diagnostic images.
  • Among all 120 interval cancers with an AI score of 10, 21% (25/120) were classified as a false negative or minimal sign significant and had AI markings matching the cancer location, suggesting they may be visible on prior screening.
  • Most of the correctly located interval cancers matched only in one view, and the majority were classified as either true negative or minimal sign non-specific, indicating low potential for being detected earlier in a real screening setting.

Article: How do AI markings on screening mammograms correspond to cancer location? An informed review of 270 breast cancer cases in BreastScreen Norway

Authors: Henrik Wethe Koch, Marthe Larsen, Hauke Bartsch, Marit Almenning Martiniussen, Bodil Margrethe Styr, Siri Fagerheim, Ingfrid Helene Salvesen Haldorsen & Solveig Hofvind

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