March 2016

Wednesday, March 2, 2016 (ECR) – Personalised medicine describes the concept of delivering the right treatment to the right patient at the right time. Personalised medicine is about the customisation of healthcare, with decisions and practices being tailored to the individual patient by use of genetic or other information, said Prof. Gabriel P. Krestin, Chairman of the Department of Radiology at Erasmus MC, University Medical Center Rotterdam, the Netherlands, ahead of the ECR 2016 press conference.

“It implies the prospect of devising a different management strategy for each individual patient. In this respect, medical imaging has always been personalised, as it provides individual assessment of the location and extent of an abnormality, whether the alteration is a disease, a malformation, or an injury,” he said.

Precision medicine, or stratification medicine, revolves around the idea that the consideration of individual characteristics – molecular and otherwise – can improve medical research and practice. Precision medicine should, therefore, integrate multiple biomarkers, based on clinical, behavioural, genomic, electrophysiological, and imaging measurements. In this context, medical imaging is intrinsically enabling precision medicine as a wide variety of new imaging techniques and methods produce important biological information about physiology, organ function, biochemistry, metabolism, molecular biology and functional genomics. These new methods combine the ability to measure and quantify biological processes with the ability to localise the measured entities into a high-quality anatomical image providing a new class of versatile and useful biomarkers. The addition of genomic data allows new correlations to be made between cellular genomics and tissue-scale imaging.

Making medicine more personalised and precise will entail increasing emphasis on, and precision in, diagnostics. Diagnoses however, depend on multiple components that include not only imaging, but also clinical observation, pathology, laboratory tests, and genomic tests. “To date, there is too little coordination between the medical specialties responsible for ordering and performing these tests, nor is there enough consideration as to the optimal order of tests. What is required is a new concept of integrated diagnostics: the convergence of imaging, pathology and laboratory tests with advanced information technology,” said Krestin.

Gabriel P. Krestin: Professor and Chairman of the Radiology Department at Erasmus Medical Centre Rotterdam, Netherlands; EIBIR Scientific Director


Thursday, March 3, 08:30–10:00, Studio 2016

PC 5 Personalised radiology: myth or reality?

  • Chairman’s introduction
    C.J. Herold; Vienna/AT
  • Personalised imaging in practice: a myth?
    F.J. Gilbert; Cambridge/UK
  • Personalised imaging and standardised protocols: a contradiction?
    S.O. Schönberg; Mannheim/DE
  • En route to personalised imaging: the role of multidisciplinary conferences
    J.A. Verschakelen; Leuven/BE
  • From personalised to precision imaging: impact on clinical practise
    G.P. Krestin; Rotterdam/NL
  • Panel discussion: How to enhance personalised radiology in clinical routine