
Differentiation of clear cell and non-clear cell renal cell carcinomas by all-relevant radiomics features from multiphase CT: a VHL mutation perspective
The main goal of this retrospective two-center study was to develop a radiomics model with all-relevant imaging features from multiphasic computed tomography (CT) for differentiating clear cell renal cell carcinoma (ccRCC) from non-ccRCC. The authors also set out to investigate the possible radiogenomics link between the imaging features and a key ccRCC driver gene—the von Hippel-Lindau (VHL) gene mutation. Using